Identification of candidate genes associated with bipolar disorder by whole-exome sequencing of a Chinese multi-affected pedigree

Identification of candidate genes associated with bipolar disorder by whole-exome sequencing of a Chinese multi-affected pedigree

Abstract Background Bipolar disorder (BD) is a severe mental disorder with high, approximately 70% heritability. Here, to identify novel risk genes of BD, we conducted whole-exome sequencing and pathway enrichment analyses across one multi-affected, southern Chinese Han pedigree. Methods Whole-exome...

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Bibliographic Details
Main Authors: Yiyang Wang, Zhen Xu, Yinnan Zhang, Hui Li
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Psychiatry
Subjects:
Bipolar disorder
NTN1
MYH10
RILP
Whole-exome sequencing
Online Access:https://doi.org/10.1186/s12888-025-07002-z
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https://doi.org/10.1186/s12888-025-07002-z

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