Molecular mechanism, diagnosis, and treatment of VACTERL association

Molecular mechanism, diagnosis, and treatment of VACTERL association

The VACTERL association is a non-random cluster of congenital malformations involving six distinct conditions: vertebral defects (V), anal atresia (A), cardiac defects (C), tracheoesophageal malformation (TE), renal defects (R), and limb anomalies (L), and is diagnosed when a fetus exhibits three or...

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Main Authors: Manluan Sun, Qiyu Zhao, Bingyu Yang, Lili Liu, Caiquan Zhou, Xinbo Yao, Jia Bu, Jiang Bian, Sai Ge, Zhuangyan Zhu, Binyu Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Pediatrics
Subjects:
VACTERL association
SHH signaling pathways
cilia-associated signaling pathways
clinical manifestations
differential diagnosis
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2025.1609624/full
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https://www.frontiersin.org/articles/10.3389/fped.2025.1609624/full

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