The Response Regulator OmpR Negatively Controls the Expression of Genes Implicated in Tilimycin and Tilivalline Cytotoxin Production in <i>Klebsiella oxytoca</i>

The Response Regulator OmpR Negatively Controls the Expression of Genes Implicated in Tilimycin and Tilivalline Cytotoxin Production in <i>Klebsiella oxytoca</i>

<i>Klebsiella oxytoca</i> toxigenic strains represent a critical health threat, mainly due to their link to antibiotic-associated hemorrhagic colitis. This serious condition results from the bacteria’s ability to produce tilimycin and tilivalline cytotoxins. Our research highlights the p...

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Main Authors: Ramón G. Varela-Nájera, Miguel A. De la Cruz, Jorge Soria-Bustos, Carmen González-Horta, Ma Carmen E. Delgado-Gardea, Jorge A. Yáñez-Santos, María L. Cedillo, Hidetada Hirakawa, James G. Fox, Blanca Sánchez-Ramírez, Miguel A. Ares
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Microorganisms
Subjects:
<i>Klebsiella oxytoca</i>
OmpR
<i>aroX</i>
<i>npsA</i>
tilimycin
tilivalline
Online Access:https://www.mdpi.com/2076-2607/13/1/158
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