1H MR Spectroscopy in Gliomatosis: Is there a Sensitivity Issue?
Objective. 1H MR spectroscopy (MRS) is widely performed for assessment of brain tumours and is considered a highly sensitive technique capable of differentiating benign from malignant conditions and tumour grading. Method. We present a case of a 69 year old woman who was suspected to have gliomatosi...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Radiology |
| Online Access: | http://dx.doi.org/10.1155/2011/371073 |
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| _version_ | 1832561101893533696 |
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| author | M. Szewczyk-Bieda A. K. Kanodia G. Main M. S. Eljamel |
| author_facet | M. Szewczyk-Bieda A. K. Kanodia G. Main M. S. Eljamel |
| author_sort | M. Szewczyk-Bieda |
| collection | DOAJ |
| description | Objective. 1H MR spectroscopy (MRS) is widely performed for assessment of brain tumours and is considered a highly sensitive technique capable of differentiating benign from malignant conditions and tumour grading. Method. We present a case of a 69 year old woman who was suspected to have gliomatosis on MRI. Results. MRS performed using single voxel and chemical shift/multivoxel techniques was within normal limits. A repeat scan 6 months later showed progressive disease, and biopsy was performed that proved the diagnosis of glioblastoma. Conclusion. Normal MRS in a patient with suspicion of gliomatosis on MRI should not reassure clinicians into assuming a benign aetiology or a good prognosis in short term. |
| format | Article |
| id | doaj-art-8dced47052de4a3eadd3a76f4ff4cebc |
| institution | Kabale University |
| issn | 2090-6862 2090-6870 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Radiology |
| spelling | doaj-art-8dced47052de4a3eadd3a76f4ff4cebc2025-02-03T01:25:57ZengWileyCase Reports in Radiology2090-68622090-68702011-01-01201110.1155/2011/3710733710731H MR Spectroscopy in Gliomatosis: Is there a Sensitivity Issue?M. Szewczyk-Bieda0A. K. Kanodia1G. Main2M. S. Eljamel3Department of Clinical Radiology, Ninewells Hospital and Medical School, NHS Tayside, Dundee DDI 9SY, UKDepartment of Clinical Radiology, Ninewells Hospital and Medical School, NHS Tayside, Dundee DDI 9SY, UKDepartment of Clinical Radiology, Ninewells Hospital and Medical School, NHS Tayside, Dundee DDI 9SY, UKDepartment of Neurosurgery, Ninewells Hospital and Medical School, NHS Tayside, Dundee DDI 9SY, UKObjective. 1H MR spectroscopy (MRS) is widely performed for assessment of brain tumours and is considered a highly sensitive technique capable of differentiating benign from malignant conditions and tumour grading. Method. We present a case of a 69 year old woman who was suspected to have gliomatosis on MRI. Results. MRS performed using single voxel and chemical shift/multivoxel techniques was within normal limits. A repeat scan 6 months later showed progressive disease, and biopsy was performed that proved the diagnosis of glioblastoma. Conclusion. Normal MRS in a patient with suspicion of gliomatosis on MRI should not reassure clinicians into assuming a benign aetiology or a good prognosis in short term.http://dx.doi.org/10.1155/2011/371073 |
| spellingShingle | M. Szewczyk-Bieda A. K. Kanodia G. Main M. S. Eljamel 1H MR Spectroscopy in Gliomatosis: Is there a Sensitivity Issue? Case Reports in Radiology |
| title | 1H MR Spectroscopy in Gliomatosis: Is there a Sensitivity Issue? |
| title_full | 1H MR Spectroscopy in Gliomatosis: Is there a Sensitivity Issue? |
| title_fullStr | 1H MR Spectroscopy in Gliomatosis: Is there a Sensitivity Issue? |
| title_full_unstemmed | 1H MR Spectroscopy in Gliomatosis: Is there a Sensitivity Issue? |
| title_short | 1H MR Spectroscopy in Gliomatosis: Is there a Sensitivity Issue? |
| title_sort | 1h mr spectroscopy in gliomatosis is there a sensitivity issue |
| url | http://dx.doi.org/10.1155/2011/371073 |
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