Simvastatin modulates osteogenic differentiation in Stem Cells isolated from Apical Papilla

Simvastatin modulates osteogenic differentiation in Stem Cells isolated from Apical Papilla

Abstract Background Simvastatin modulates numerous stem cell functions, including stemness maintenance and differentiation. The present study aimed to explore the effect of simvastatin on the osteogenic differentiation of Stem Cells isolated from Apical Papilla (SCAPs) in vitro. Methods Cells were i...

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Main Authors: Paak Rewthamrongsris, Suphalak Phothichailert, Uraiwan Chokechanachaisakul, Prim Janjarussakul, Chatvadee Kornsuthisopon, Lakshman Samaranayake, Thanaphum Osathanon
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Oral Health
Subjects:
Stem cells from apical papilla
Simvastatin
Cell viability
Cell proliferation
Cell migration
Online Access:https://doi.org/10.1186/s12903-025-05721-z
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https://doi.org/10.1186/s12903-025-05721-z

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