Transcriptomic and Metabolomic Analysis Reveals Multifaceted Impact of Gcn5 Knockdown in <i>Drosophila</i> Development

Transcriptomic and Metabolomic Analysis Reveals Multifaceted Impact of Gcn5 Knockdown in <i>Drosophila</i> Development

<b>Background:</b> General control nonderepressible 5 (Gcn5) is a lysine acetyltransferase (KAT) that is evolutionarily conserved across eukaryotes, with two homologs (Kat2a and Kat2b) identified in humans and one (Gcn5) in <i>Drosophila</i>. Gcn5 contains a P300/CBP-associat...

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Main Authors: Youfeng Li, Yue Xu, Ruike Li, Sirui Huang, Qiong Wu, Jing Yan, Zhigang Jiang, Xiushan Wu, Fang Li, Yuequn Wang, Yongqing Li, Xiongwei Fan, Wuzhou Yuan
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Metabolites
Subjects:
Gcn5
knockdown
transcriptome
metabolome
<i>Drosophila</i>
pupation
Online Access:https://www.mdpi.com/2218-1989/14/12/680
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