LL37 promotes angiogenesis: a potential therapeutic strategy for lower limb ischemic diseases

PurposeTo study the angiogenic capacity of antimicrobial peptide LL37 (cathelicidin antimicrobial peptide), explore its molecular mechanisms, and provide new ideas for treating lower limb ischemic diseases.MethodsLL37 was applied exogenously to human umbilical vein endothelial cells (HUVECs), and it...

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Bibliographic Details
Main Authors: Yingying Yang, Gang Wu, Yini Wang, Qiancheng Mao, Dongxu Zhang, Jitao Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1587351/full
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