Effects and Persistence of Bifidobacterium animalis subsp. lactis BL-99 and Fructooligosaccharides on Older Adults with Functional Constipation: A Randomized, Double-Blind, Placebo-Controlled Trial

Effects and Persistence of Bifidobacterium animalis subsp. lactis BL-99 and Fructooligosaccharides on Older Adults with Functional Constipation: A Randomized, Double-Blind, Placebo-Controlled Trial

Research on effects of synbiotics in older adults with functional constipation (FC) is limited. This randomized, double-blind, placebo-controlled trial evaluated a 4-week synbiotic (Bifidobacterium animalis subsp. lactis BL-99 and fructooligosaccharides [FOS]) intervention in 67 participants ≥60 yea...

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Main Authors: Meina Li, Qi Zhang, Wen Zhao, Juan Chen, Yinghua Liu, Limian Zhou, Yihui Liu, Langrun Wang, Yiran Guan, Jian He, Qiuyue Jiang, Zhaozhong Zeng, Xinmei Guo, Can Liu, Liwei Zhang, Yong Zhang, Jie Luo, Wei-Lian Hung, Jingjing He, Ran Wang
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:The Journal of Nutrition, Health and Aging
Subjects:
Synbiotics
Probiotics
Functional constipation
Older adults
Gut Microbiota
Online Access:http://www.sciencedirect.com/science/article/pii/S127977072500123X
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