ROS-responsive nanoparticles for bioimaging and treating acute lung injury by releasing dexamethasone and improving alveolar macrophage homeostasis

ROS-responsive nanoparticles for bioimaging and treating acute lung injury by releasing dexamethasone and improving alveolar macrophage homeostasis

Abstract Background Acute lung injury (ALI) triggers the activation of pulmonary macrophages, which in turn produce excessive amounts of reactive oxygen species (ROS). Results We synthesized ROS-responsive red light-emitting carbon dots (RCMNs) that target lung macrophages, possess bioimaging capabi...

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Bibliographic Details
Main Authors: Wenna Fan, Yongyao Tang, Yamin Liu, Ya Ran, Guangrui Pan, Xin Song, Li Mai, Xue Jiang, Dan Chen, Fangzhou Song, Haiyu Li
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Nanobiotechnology
Subjects:
Acute lung injury
RCMNs nanoparticle
Alveolar macrophages
Mitochondrial function
Online Access:https://doi.org/10.1186/s12951-024-03015-0
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https://doi.org/10.1186/s12951-024-03015-0

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