Deep exploration of logical models of cell differentiation in human preimplantation embryos

Abstract The advent of single-cell transcriptomics (scRNA-seq) has provided unprecedented access to specific cell type signatures, including during transient developmental stages. One key expectation is to be able to model gene regulatory networks (GRNs) from the cell-type scRNA-seq signatures. Howe...

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Bibliographic Details
Main Authors: Mathieu Bolteau, Célia Messaoudi, Laurent David, Jérémie Bourdon, Carito Guziolowski
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-025-00537-7
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