Development of a Disease Modeling Framework for Glutamatergic Neurons Derived from Neuroblastoma Cells in 3D Microarrays

Development of a Disease Modeling Framework for Glutamatergic Neurons Derived from Neuroblastoma Cells in 3D Microarrays

Abstract Neurodegenerative diseases (NDDs) present significant challenges due to limited treatment options, ethical concerns surrounding traditional animal models, and the time-consuming and costly process of using human-induced pluripotent stem cells (iPSCs). We addressed these issues by developing...

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Bibliographic Details
Main Authors: Duc Long Nguyen, My Phuong Thi Le, Kyung Won Lee, Jae-Ho Kim, Hyun C. Yoon, Huyen T. M. Pham
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
SH-SY5Y cells
3D microarrays
Glutamatergic neuron
Disease modeling
Retinoic acid
Online Access:https://doi.org/10.1038/s41598-024-80369-3
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https://doi.org/10.1038/s41598-024-80369-3

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