The development of a novel multiepitope vaccine targeting the secretion systems of Pseudomonas aeruginosa using a reverse vaccinology and immunoinformatic strategy

Abstract The emergence of multidrug-resistant Pseudomonas aeruginosa strains poses a significant public health risk due to the high morbidity and mortality associated with invasive infections. Despite extensive efforts, vaccine candidates targeting P. aeruginosa have failed in clinical trials, and t...

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Bibliographic Details
Main Authors: Tohid Piri-Gharaghie, Marjaneh Ebrahimi, Behnaz Dehganzad, Zahra Seraj
Format: Article
Language:English
Published: Springer 2025-04-01
Series:Discover Applied Sciences
Subjects:
Online Access:https://doi.org/10.1007/s42452-025-06768-x
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