$Liposomal irinotecan with fluorouracil and leucovorin as salvage treatment for advanced biliary tract cancer refractory to gemcitabine and cisplatin$

Liposomal irinotecan with fluorouracil and leucovorin as salvage treatment for advanced biliary tract cancer refractory to gemcitabine and cisplatin

IntroductionThe combination of liposomal irinotecan with fluorouracil and leucovorin (Nal-IRI/FL) has shown efficacy in phase II trials for advanced biliary tract cancer (BTC) following gemcitabine-cisplatin (GP) therapy. However, its effectiveness and safety in real-world clinical settings have not...

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Main Authors:	Hyunho Kim, Kabsoo Shin, Hyung Soon Park, Tae Ho Hong, Younghoon Kim, Sung Hak Lee, In-Ho Kim, MyungAh Lee, Se Jun Park
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-08-01
Series:	Frontiers in Oncology
Subjects:	biliary tract cancer liposomal irinotecan second-line chemotherapy real-world evidence survival outcome
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1638606/full
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