Liposomal irinotecan with fluorouracil and leucovorin as salvage treatment for advanced biliary tract cancer refractory to gemcitabine and cisplatin

Liposomal irinotecan with fluorouracil and leucovorin as salvage treatment for advanced biliary tract cancer refractory to gemcitabine and cisplatin

IntroductionThe combination of liposomal irinotecan with fluorouracil and leucovorin (Nal-IRI/FL) has shown efficacy in phase II trials for advanced biliary tract cancer (BTC) following gemcitabine-cisplatin (GP) therapy. However, its effectiveness and safety in real-world clinical settings have not...

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Bibliographic Details
Main Authors: Hyunho Kim, Kabsoo Shin, Hyung Soon Park, Tae Ho Hong, Younghoon Kim, Sung Hak Lee, In-Ho Kim, MyungAh Lee, Se Jun Park
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Oncology
Subjects:
biliary tract cancer
liposomal irinotecan
second-line chemotherapy
real-world evidence
survival outcome
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1638606/full
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https://www.frontiersin.org/articles/10.3389/fonc.2025.1638606/full

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