Grin2a Hypofunction Impairs Spatial Working Memory and Disrupts Hippocampal Network Oscillations and Excitatory-Inhibitory Balance

Background: NMDA receptors, particularly those containing the GluN2A subunit, are critical for hippocampal-dependent learning and memory. The GluN2A subunit is encoded by the GRIN2A gene and is essential for maintaining cognitive function, including working memory. In this study, we explored how ful...

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Bibliographic Details
Main Authors: Hassan Hosseini, Sky Evans-Martin, Emma Bogomilsky, Dominique L. Pritchett, Kevin S. Jones
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Biological Psychiatry Global Open Science
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667174325000540
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