Impact of a mobile health intervention on health management among children with phenylketonuria based on a multi-theory model of the behavior change wheel theory and family health theory: protocol for a randomized controlled trial

BackgroundPhenylketonuria (PKU) is a hereditary metabolic disorder caused by mutations in the phenylalanine hydroxylase (PAH) gene, leading to the accumulation of phenylalanine (Phe) in the blood. Without timely treatment, PKU patients may develop irreversible intellectual and neurocognitive deficit...

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Main Authors: Jie Wang, Sihan Yang, Jing Wang, Bo Zhu, Yan Wang, Lirong Zhao, Wenli Wang, Ge Li, Fei Wang, Xiaohua Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Psychiatry
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Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1583804/full
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