Nanostructured Strategies for Melanoma Treatment—Part II: Targeted Topical Delivery of Curcumin via Poloxamer-Based Thermosensitive Hydrogels

Nanostructured Strategies for Melanoma Treatment—Part II: Targeted Topical Delivery of Curcumin via Poloxamer-Based Thermosensitive Hydrogels

<b>Background/Objectives</b>: Curcumin (CUR) is a natural compound with notable antitumor properties but faces limitations in topical applications due to poor aqueous solubility, instability, and insufficient skin penetration. To overcome these challenges, a nanomicellar formulation (TPG...

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Bibliographic Details
Main Authors: Valentina Paganini, Daniela Monti, Patrizia Chetoni, Susi Burgalassi, Andrea Cesari, Fabio Bellina, Silvia Tampucci
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Pharmaceuticals
Subjects:
curcumin
thermosensitive hydrogel
nanocarrier
topical melanoma therapy
skin delivery
polymeric micelles
Online Access:https://www.mdpi.com/1424-8247/18/3/337
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