Ameliorative effects of agomelatine against doxorubicin-induced hepatotoxicity

Ameliorative effects of agomelatine against doxorubicin-induced hepatotoxicity

Abstract Drug-induced hepatotoxicity is a significant impediment to the use of doxorubicin, a commonly employed chemotherapeutic agent with established efficacy in cancer treatment. The present study aimed to determine the potential protective effects of agomelatine against doxorubicin hepatotoxicit...

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Bibliographic Details
Main Authors: Hasan Basri Savas, Mehmet Enes Sozen, Gokhan Cuce, Tuba Batur
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Pharmacology and Toxicology
Subjects:
Doxorubicin
Hepatotoxicity
Agomelatine
Oxidative stress
Caspase-3
Online Access:https://doi.org/10.1186/s40360-025-00988-y
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https://doi.org/10.1186/s40360-025-00988-y

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