Basal Secretion of Lysozyme from Human Airways in Vitro
The aim of this study was to examine the basal release of lysozyme from isolated human lung tissues. Measurements of lysozyme in the fluids derived from lung preparations were performed using a rate-of-lysis assay subsequent to acidification of the biological samples. Lysozyme released from bronchia...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
1999-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1080/09629359990333 |
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| _version_ | 1832563577869828096 |
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| author | Patricia Roger Jean-Pierre Gascard Vincent Thomas de Montpreville Charles Brink |
| author_facet | Patricia Roger Jean-Pierre Gascard Vincent Thomas de Montpreville Charles Brink |
| author_sort | Patricia Roger |
| collection | DOAJ |
| description | The aim of this study was to examine the basal release of lysozyme from isolated human lung tissues. Measurements of lysozyme in the fluids derived from lung preparations were performed using a rate-of-lysis assay subsequent to acidification of the biological samples. Lysozyme released from bronchial preparations into fluids was greater than that observed for parenchymal tissues. The lysozyme quantities detected in bronchial fluids were not modified by removal of the surface epithelium. Furthermore, the quantities of lysozyme in bronchial fluids was correlated with the size of the bronchial preparations. These results suggest that the lysozyme was principally secreted by the human bronchi (submucosal layer) rather than by parenchyma tissues and that a greater release was observed in the proximal airways. |
| format | Article |
| id | doaj-art-8cb851fb0a534d3c81476af8086b5aec |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 1999-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-8cb851fb0a534d3c81476af8086b5aec2025-02-03T01:13:12ZengWileyMediators of Inflammation0962-93511466-18611999-01-018631932310.1080/09629359990333Basal Secretion of Lysozyme from Human Airways in VitroPatricia Roger0Jean-Pierre Gascard1Vincent Thomas de Montpreville2Charles Brink3Laboratoire de Pharmacologie Pulmonaire, CNRS-ESA 8078, FranceLaboratoire de Pharmacologie Pulmonaire, CNRS-ESA 8078, FranceLaboratoire d'Anatomopathologie, Hôpital Marie Lannelongue, 133 Av de la Résistance, Le Plessis Robinson, 92350, FranceLaboratoire de Pharmacologie Pulmonaire, CNRS-ESA 8078, FranceThe aim of this study was to examine the basal release of lysozyme from isolated human lung tissues. Measurements of lysozyme in the fluids derived from lung preparations were performed using a rate-of-lysis assay subsequent to acidification of the biological samples. Lysozyme released from bronchial preparations into fluids was greater than that observed for parenchymal tissues. The lysozyme quantities detected in bronchial fluids were not modified by removal of the surface epithelium. Furthermore, the quantities of lysozyme in bronchial fluids was correlated with the size of the bronchial preparations. These results suggest that the lysozyme was principally secreted by the human bronchi (submucosal layer) rather than by parenchyma tissues and that a greater release was observed in the proximal airways.http://dx.doi.org/10.1080/09629359990333 |
| spellingShingle | Patricia Roger Jean-Pierre Gascard Vincent Thomas de Montpreville Charles Brink Basal Secretion of Lysozyme from Human Airways in Vitro Mediators of Inflammation |
| title | Basal Secretion of Lysozyme from Human Airways in Vitro |
| title_full | Basal Secretion of Lysozyme from Human Airways in Vitro |
| title_fullStr | Basal Secretion of Lysozyme from Human Airways in Vitro |
| title_full_unstemmed | Basal Secretion of Lysozyme from Human Airways in Vitro |
| title_short | Basal Secretion of Lysozyme from Human Airways in Vitro |
| title_sort | basal secretion of lysozyme from human airways in vitro |
| url | http://dx.doi.org/10.1080/09629359990333 |
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