An efficient strategy for heterologous expression and purification of active peptide hainantoxin-IV.

An efficient strategy for heterologous expression and purification of active peptide hainantoxin-IV.

Hainantoxin-IV (HNTX-IV) from the venom of the spider Selenocosmia hainana is a potent antagonist that specifically inhibits the tetrodotoxin-sensitive (TTX-S) sodium channels. The toxin peptide consists of 35 amino acids and adopts a typical inhibitory cystine knot (ICK) motif. To obtain adequate H...

Full description

Saved in:
Bibliographic Details
Main Authors: Hui Zhang, Peng-Fei Huang, Er Meng, Wen-Ying Li, Lu Zhou, Ling-Yun Zhu, Lei Wu, Meng-Jie Li, Song-Ping Liang, Dong-Yi Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0117099&type=printable
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0117099&type=printable

Similar Items