Excess A-subunits of Shiga toxin 2a are produced in enterohemorrhagic Escherichia coli

Excess A-subunits of Shiga toxin 2a are produced in enterohemorrhagic Escherichia coli

Abstract Shiga toxins (Stx) produced by Shiga toxin-producing Escherichia coli (STEC) and enterohemorrhagic E. coli (EHEC) are ribosome-inactivating AB5 proteins that consist of one enzymatic active A-subunit (StxA) and a pentamer of non-covalently linked B-subunits (StxB). The description of Stx as...

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Bibliographic Details
Main Authors: Katrin Neudek, Theresa Kunz, Holger Barth, Herbert Schmidt
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Shiga toxins
Enterohemorrhagic Escherichia coli
AB5 toxins
Gene expression
Toxin production
Online Access:https://doi.org/10.1038/s41598-025-01342-2
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https://doi.org/10.1038/s41598-025-01342-2

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