Influence of Hedgehog signaling pathway activation on calvarial defect healing in type I diabetic mice

Influence of Hedgehog signaling pathway activation on calvarial defect healing in type I diabetic mice

Objective This study aimed to elucidate the mechanisms underlying the impaired bone healing capacity in type 1 diabetes (T1DM) by investigating the role of the Hedgehog (Hh) signaling pathway in the impaired healing of cranial defects caused by T1DM. Methods This study was approved by the experiment...

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Bibliographic Details
Main Author: WU Yingzhang, LIU Linan, LIU Shibo, HU Pei, LUO En
Format: Article
Language:zho
Published: Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases 2025-07-01
Series:口腔疾病防治
Subjects:
type i diabetes|high-glucose environment|akita mouse model|cranial defects|hedgehog signaling pathway|smoothened agonist|osteocalcin|osteogenic differentiation
Online Access:https://www.kqjbfz.com/fileup/2096-1456/PDF/2096-1456（2025）07-0542-12.pdf
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https://www.kqjbfz.com/fileup/2096-1456/PDF/2096-1456（2025）07-0542-12.pdf

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