mRNA stability fine-tunes gene expression in the developing cortex to control neurogenesis.

RNA abundance is controlled by rates of synthesis and degradation. Although mis-regulation of RNA turnover is linked to neurodevelopmental disorders, how it contributes to cortical development is largely unknown. Here, we discover the landscape of RNA stability regulation in the cerebral cortex and...

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Bibliographic Details
Main Authors: Lucas D Serdar, Jacob R Egol, Brad Lackford, Brian D Bennett, Guang Hu, Debra L Silver
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-02-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3003031
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