Electrophysiological Signatures in Global Cerebral Ischemia: Neuroprotection Via Chemogenetic Inhibition of CA1 Pyramidal Neurons in Rats

Electrophysiological Signatures in Global Cerebral Ischemia: Neuroprotection Via Chemogenetic Inhibition of CA1 Pyramidal Neurons in Rats

Background Although there has been limited research into the perturbation of electrophysiological activity in the brain after ischemia, the activity signatures during ischemia and reperfusion remain to be fully elucidated. We aim to comprehensively describe these electrophysiological signatures and...

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Bibliographic Details
Main Authors: Penglai Liu, Jiang Xu, Yilan Chen, Qi Xu, Wei Zhang, Bin Hu, Anan Li, Qiuju Zhu
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
astrocyte activation
chemogenetic modulation
global cerebral ischemia
in vivo electrophysiology
ischemic damage
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.124.036146
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https://www.ahajournals.org/doi/10.1161/JAHA.124.036146

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