Co-delivery of anti-inflammatory and antioxidant agents via polymersomes for osteoarthritis therapy

BackgroundOsteoarthritis (OA) is a chronic degenerative joint disease primarily driven by inflammation and oxidative stress. This study aimed to develop a polymersome-based co-delivery system encapsulating hydrophilic cordycepin and hydrophobic phenylboronic acid (PBA) to enhance their solubility, s...

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Bibliographic Details
Main Authors: Mengjie Rui, Li Wang, Ke Mi, Yinfeng Li, Naying Fang, Yingying Ge, Qiuqi Feng, Yaqi Luo, Chunlai Feng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1635761/full
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