Prophylaxis for renal patients at risk of COVID-19 infection: results from the intranasal niclosamide randomised, double blinded, placebo controlled arm of the PROTECT-V platform trial

Prophylaxis for renal patients at risk of COVID-19 infection: results from the intranasal niclosamide randomised, double blinded, placebo controlled arm of the PROTECT-V platform trial

Abstract Purpose Despite vaccination, many patients remain vulnerable to COVID-19 infection and poorer outcomes, because of underlying health conditions resulting in sub-optimal vaccine responses. This study aims to demonstrate whether intranasal niclosamide confers additional protection against COV...

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Main Authors: Toby J. L. Humphrey, Wendi Qian, Michael Chen-Xu, Francis Dowling, Katrina Gatley, Rakshya Adhikari, Tracey Hensman, Louise Stockley, Abhinav Bassi, Nikita Bathla, Indranil Dasgupta, Davinder P. S. Dosanjh, Mads Jellingsø, Per Sørensen, Morten Lind Jensen, Anne Weibel Callesen, John R. Bradley, Vivekanand Jha, Morten O. A. Sommer, Thomas F. Hiemstra, Rona M. Smith, PROTECT-V consortium
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Infectious Diseases
Subjects:
COVID-19
Prophylaxis
Renal
Clinical trial
Online Access:https://doi.org/10.1186/s12879-025-10584-4
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https://doi.org/10.1186/s12879-025-10584-4

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