The prognostic significance of MMP-8 tissue Immunoexpression in pancreatic ductal adenocarcinoma after neoadjuvant therapy

The prognostic significance of MMP-8 tissue Immunoexpression in pancreatic ductal adenocarcinoma after neoadjuvant therapy

Abstract Neoadjuvant therapy (NAT) has become increasingly common in pancreatic ductal adenocarcinoma (PDAC). Still, PDAC remains one of the deadliest cancers and clinically useful biomarkers are needed. Matrix metalloproteinase 8 (MMP-8) has previously been identified as a potential biomarker for P...

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Bibliographic Details
Main Authors: Ella Kesti, Annika Eurola, Mirjami Kaasinen, Harri Mustonen, Jaana Hagström, Timo Sorsa, Ari Ristimäki, Hanna Seppänen, Caj Haglund, Malin Sund
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
PDAC
Neoadjuvant therapy
Matrix metalloproteinase 8
Online Access:https://doi.org/10.1038/s41598-025-10538-5
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https://doi.org/10.1038/s41598-025-10538-5

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