Evolution of the PRNT: Merging tradition and innovation to set the gold standard in the era of automation

Evolution of the PRNT: Merging tradition and innovation to set the gold standard in the era of automation

The plaque reduction neutralization test (PRNT) is the gold standard for quantifying neutralizing antibodies owing to its high sensitivity and specificity. Widely used in seroepidemiological studies and vaccine development, PRNT is limited by labor-intensive procedures, reliance on highly skilled st...

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Bibliographic Details
Main Authors: Caio Denani, Ingrid Horbach, Bruno Setatino, Adriana Azevedo, Sheila Lima, Waleska Schwarcz, Ivanildo Sousa
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
PRNT
automation
neutralizing antibodies
vaccine development
Online Access:https://www.tandfonline.com/doi/10.1080/21645515.2025.2528368
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https://www.tandfonline.com/doi/10.1080/21645515.2025.2528368

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