Somatosensory and prefrontal cortex activity relates to emotional outcomes and hair cortisol concentration in chronic postsurgical pain

Somatosensory and prefrontal cortex activity relates to emotional outcomes and hair cortisol concentration in chronic postsurgical pain

Abstract Chronic post-surgical pain (CPSP) poses significant socioeconomic and humanitarian challenges. This study investigated relationships between resting-state neural activation in the somatosensory cortex (SMC) and emotional functioning outcomes (depression, anxiety, perceived stress), and betw...

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Bibliographic Details
Main Authors: Margaret Moreland, Caitlin Curry, Anthony Wang, Madison Vansickel, Ziyan Wu, Christine B. Sieberg
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Chronic post-surgical pain
Functional near-infrared spectroscopy
Chronic stress
Hair cortisol
Tissue saturation index
Somatosensory cortex
Online Access:https://doi.org/10.1038/s41598-025-00685-0
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https://doi.org/10.1038/s41598-025-00685-0

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