Functionally graded scaffold with M2 macrophage-derived LncRNA-Encoded peptide: Mechanistic and therapeutic evaluation for rotator cuff repair

Functionally graded scaffold with M2 macrophage-derived LncRNA-Encoded peptide: Mechanistic and therapeutic evaluation for rotator cuff repair

The rotator cuff is prone to tear under degenerative changes or mechanical injury, leading to excessive inflammation, extracellular matrix degradation, and unsatisfactory prognosis. Interleukin-4 (IL-4) was used to induce macrophages polarization toward M2 phenotype. By mapping IL 4-activated pathwa...

Full description

Saved in:
Bibliographic Details
Main Authors: Hao Feng, Gonghao Zhang, Li Xiong, Panpan Shang, Xiao Yu, Bin Chai, Lu Han, Shuqi Lou, Muhammad Shafiq, Yiying Zhang, Mohamed EL-Newehy, Meera Moydeen Abdulhameed, Zhengchao Yuan, Xiumei Mo, Yunhan Ji
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-10-01
Series:Bioactive Materials
Subjects:
Electrospinning
Rotator cuff
Tendon-bone interface
LncRNA MM2P
MDP1
Anti-inflammatory
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X25002683
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S2452199X25002683

Similar Items