A multicenter single-arm clinical study of Chinese children’s cancer group-acute promyelocytic leukemia-2017 (CCCG-APL-2017) protocol

A multicenter single-arm clinical study of Chinese children’s cancer group-acute promyelocytic leukemia-2017 (CCCG-APL-2017) protocol

Abstract The Realgar-Indigo Naturalis formula (RIF) is a proprietary Chinese medicine, which is one of the important drugs in the treatment of pediatric acute promyelocytic leukemia (APL). However, the dose of RIF in clinical application is not uniform and the long-term effectiveness and safety of c...

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Main Authors: Lixian Chang, Ju Gao, Xiaoying Lei, Yingyi He, Shuquan Zhuang, Chunhuai Li, Kaizhi Weng, Lingzhen Wang, Xia Guo, Qihui Liu, Pengfei Wang, Yong Zhuang, Mei Yan, Wei Liu, Hui Chen, Min Zhang, Shuhong Shen, Xiaofan Zhu, Xiuli Ju, Li Zhang, Zhuo Wang
Format: Article
Language:English
Published: Nature Publishing Group 2025-08-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-025-02353-1
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https://doi.org/10.1038/s41392-025-02353-1

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