C-X-C motif chemokine ligand 1 derived from oral squamous cell carcinoma promotes cancer-associated fibroblast differentiation and tumor growth
Abstract Cancer-associated fibroblasts (CAFs), the predominant stromal cells in the tumor microenvironment (TME), play a critical role in the progression of solid tumors, including oral squamous cell carcinoma (OSCC). However, the molecular mechanisms by which OSCC-derived factors mediate CAF differ...
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| Main Authors: | Soon Chul Heo, In-hye Nam, Bo Ram Keum, Yeo Gyun Yun, Jae-Yeol Lee, Hyung Joon Kim |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-06-01
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| Series: | Molecular Biomedicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43556-025-00281-8 |
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