Integrin beta‐like 1 is regulated by DNA methylation and increased in heart failure patients

Integrin beta‐like 1 is regulated by DNA methylation and increased in heart failure patients

Abstract Aims Dynamic alterations in cardiac DNA methylation have been implicated in the development of heart failure (HF) with evidence of ischaemic heart disease (IHD); however, there is limited research into cell specific, DNA methylation sensitive genes that are affected by dysregulated DNA meth...

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Main Authors: Lauren Kerrigan, Kevin Edgar, Adam Russell‐Hallinan, Oisin Cappa, Nadezhda Glezeva, Carlos Galan‐Arriola, Eduardo Oliver, Borja Ibanez, John Baugh, Patrick Collier, Mark Ledwidge, Ken McDonald, David Simpson, Sudipto Das, David J. Grieve, Chris J. Watson
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:ESC Heart Failure
Subjects:
Heart failure
Ischaemic cardiomyopathy
Epigenetics
DNA methylation
Single nuclei RNA sequencing: cardiac fibroblasts
Online Access:https://doi.org/10.1002/ehf2.15050
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https://doi.org/10.1002/ehf2.15050

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