Characterizing SSTR2 expression and modulation for targeted imaging and therapy in preclinical models of triple-negative breast cancer

Characterizing SSTR2 expression and modulation for targeted imaging and therapy in preclinical models of triple-negative breast cancer

Abstract Patients with breast cancer which lack molecular targets, such as human epidermal growth factor receptor 2 (HER2) or hormone receptors, have limited access to targeted therapies. Somatostatin receptor 2 (SSTR2) is overexpressed in some cancers, and SSTR2-targeted radiopharmaceuticals are FD...

Full description

Saved in:
Bibliographic Details
Main Authors: Shannon E. Lynch, Corinne I. Crawford, Hailey A. Houson, James M. Omweri, Piyasuda Pukkanasut, Carlos A. Gallegos, Jason D. Whitt, Renata Jaskula-Sztul, Suzanne E. Lapi, Anna G. Sorace
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
PET
Breast cancer
SSTR2
SAHA
HDAC
Preclinical
Online Access:https://doi.org/10.1038/s41598-025-94578-x
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/s41598-025-94578-x

Similar Items