Fiber-specific differences in protein content of pathways related to mTORC1 signaling and oxidative metabolism in individuals with obesity

Fiber-specific differences in protein content of pathways related to mTORC1 signaling and oxidative metabolism in individuals with obesity

Abstract This study aimed to compare the protein content of pathways related to mTORC1 signaling and oxidative metabolism in whole skeletal muscle and isolated muscle fibers from healthy individuals (HEALTHY) and individuals with obesity (OBESE). Muscle biopsies were obtained from 18 individuals. Sa...

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Bibliographic Details
Main Authors: Cristian Campos, Marcelo Flores-Opazo, Denisse Valladares-Ide, Claudio Cabello-Verrugio, Pilar Parada, Francisco Morales, Joseline Arredondo, Luis Peñailillo
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Skeletal muscle
Muscle ubiquitination
Muscle protein synthesis
Mitochondrial complex
Overweight
Online Access:https://doi.org/10.1038/s41598-025-09169-7
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https://doi.org/10.1038/s41598-025-09169-7

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