Myostatin-driven muscle hypertrophy: a double-edged sword in muscle physiology

Abstract Myostatin (MSTN), a pivotal regulator of skeletal muscle homeostasis, belongs to the TGF-β family and functions as a potent inhibitor of muscle hypertrophy. While physiological muscle hypertrophy is a normal adaptive response, dysregulated or excessive hypertrophy often resulting from myost...

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Bibliographic Details
Main Authors: Ghisaram Dewasi, Parikshit Nagda, Gurusha Bahl, Vivek Jain, Sanjay Kumar Gupta
Format: Article
Language:English
Published: Springer 2025-08-01
Series:Journal of Rare Diseases
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Online Access:https://doi.org/10.1007/s44162-025-00086-x
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