Assessment of targeted and non-targeted responses in cells deficient in ATM function following exposure to low and high dose X-rays.
Radiation sensitivity at low and high dose exposure to X-rays was investigated by means of chromosomal aberration (CA) analysis in heterozygous ATM mutation carrier and A-T patient (biallelic ATM mutation) lymphoblastoid cell lines (LCLs). Targeted and non-targeted responses to acutely delivered irr...
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| Main Authors: | Anne Kiuru, Meerit Kämäräinen, Sirpa Heinävaara, Katri Pylkäs, Kim Chapman, Armi Koivistoinen, Teuvo Parviainen, Robert Winqvist, Munira Kadhim, Virpi Launonen, Carita Lindholm |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0093211&type=printable |
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