A point-of-research decision in synovial tissue engineering: Mesenchymal stromal cells, tissue derived fibroblast or CTGF-mediated mesenchymal-to-fibroblast transition

Rheumatoid arthritis (RA) and osteoarthritis (OA) are prevalent inflammatory joint diseases characterized by synovitis, cartilage, and bone destruction. Fibroblast-like synoviocytes (FLSs) of the synovial membrane are a decisive factor in arthritis, making them a target for future therapies. Develop...

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Bibliographic Details
Main Authors: Alexandra Damerau, Marieluise Kirchner, Philipp Mertins, Frank Buttgereit, Timo Gaber
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:European Journal of Cell Biology
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Online Access:http://www.sciencedirect.com/science/article/pii/S0171933524000724
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