Inhibition of energy metabolism in macrophages to block MPS for enhancing the chemotherapy efficacy

Various biological barriers hinder the effective use of administered nanoparticles, with the mononuclear phagocyte system (MPS) being a major obstacle to their in vivo efficacy. Glucose metabolism is an important factor for macrophages to perform MPS clearance in vivo. In this study, energy metaboli...

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Bibliographic Details
Main Authors: Li Bin, Linlin Huang, Aiyu Chen, Yinyi Yang, Yanmei Zheng, Hanwen Zhang, Qinfang Zhang, Jiahui Zheng, Meiting Qiu, Xiajin Li, Yangbo Tan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Bioengineering and Biotechnology
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Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1549101/full
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