Comparing the effectiveness of pterostilbene and sitagliptin on modulating inflammatory levels and inducing autophagy to improve atherosclerosis outcome: A preclinical study in rabbits [version 4; peer review: 2 approved]

Comparing the effectiveness of pterostilbene and sitagliptin on modulating inflammatory levels and inducing autophagy to improve atherosclerosis outcome: A preclinical study in rabbits [version 4; peer review: 2 approved]

Background Inflammation is the key contributor to the development of atherosclerotic plague. This study aims to evaluate the protective and autophagy induction properties of pterostilbene and sitagliptin on modulating the degree of atherosclerosis in rabbit models treated with an atherogenic diet. M...

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Bibliographic Details
Main Authors: Wisam J Mohammed, Azhar Al-Shaibany, Anil K Philip, Hussam H Sahib, Hayder A Al-Aubaidy, Najah R Hadi, Dina A Jamil, Bassim I Mohammad
Format: Article
Language:English
Published: F1000 Research Ltd 2025-05-01
Series:F1000Research
Subjects:
Pterostilbene
Sitagliptin
Atherosclerosis
PI3K
AMPK
AKT
eng
Online Access:https://f1000research.com/articles/12-339/v4
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