Modeling the use of transient ligand binding information by AMPA receptors
Abstract Glutamate mediates fast excitatory neurotransmission through α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA)-type glutamate receptors in the central nervous system. Although it is well known that the glutamate affinity for AMPA receptors is submicromolar, ligand-dependent curre...
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| Main Authors: | Helena Braunstein, Alejandra C. Ventura, Alejandro Colman-Lerner |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | npj Systems Biology and Applications |
| Online Access: | https://doi.org/10.1038/s41540-025-00546-6 |
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