Allosteric binding sites in Rab11 for potential drug candidates.

Allosteric binding sites in Rab11 for potential drug candidates.

Rab11 is an important protein subfamily in the RabGTPase family. These proteins physiologically function as key regulators of intracellular membrane trafficking processes. Pathologically, Rab11 proteins are implicated in many diseases including cancers, neurodegenerative diseases and type 2 diabetes...

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Bibliographic Details
Main Authors: Ammu Prasanna Kumar, Suryani Lukman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pone.0198632/1/pone.0198632.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20210223%2Fauto%2Fstorage%2Fgoog4_request&X-Goog-Date=20210223T072346Z&X-Goog-Expires=3600&X-Goog-SignedHeaders=host&X-Goog-Signature=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