The hazard of using the Poisson model to cope with immortal time bias in the case of time-varying hazard

The hazard of using the Poisson model to cope with immortal time bias in the case of time-varying hazard

Abstract Background A time-dependent analysis, usually by means of Poisson and Cox regression models, can be applied to prevent immortal time bias. However, the use of the Poisson model requires the assumption that the event rate is constant over time. This study aims to assess the potential consequ...

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Bibliographic Details
Main Authors: Federico Rea, Gabriella Morabito, Giovanni Corrao, Anna Cantarutti
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Medical Research Methodology
Subjects:
Immortal time bias
Poisson model
Cox Model
Time-varying risk
Simulation study
Online Access:https://doi.org/10.1186/s12874-024-02396-y
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https://doi.org/10.1186/s12874-024-02396-y

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