Physiologically Based Toxicokinetic Modelling as a Tool to Support Risk Assessment: Three Case Studies

In this contribution we present three case studies of physiologically based toxicokinetic (PBTK) modelling in regulatory risk assessment. (1) Age-dependent lower enzyme expression in the newborn leads to bisphenol A (BPA) blood levels which are near the levels of the tolerated daily intake (TDI) at...

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Bibliographic Details
Main Authors: Hans Mielke, Ursula Gundert-Remy
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Journal of Toxicology
Online Access:http://dx.doi.org/10.1155/2012/359471
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