Study of the Influence of Pharmaceutical Excipients on the Solubility and Permeability of BCS Class II Drugs

Study of the Influence of Pharmaceutical Excipients on the Solubility and Permeability of BCS Class II Drugs

Most novel active pharmaceutical ingredients have low water solubility; therefore, solubility-enhancing methods are applied. The aim of the present investigation is to study the impact of nine commonly used pharmaceutical excipients (fillers, surfactants, cyclodextrins, polymers) on solubility, perm...

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Bibliographic Details
Main Authors:	Vivien Bárdos, Rita Szolláth, Petra Tőzsér, Arash Mirzahosseini, Bálint Sinkó, Réka Angi, Krisztina Takács-Novák
Format:	Article
Language:	English
Published:	MDPI AG 2025-04-01
Series:	Scientia Pharmaceutica
Subjects:	BCS II APIs pharmaceutical excipients SSF PAMPA equilibrium solubility intestinal permeability
Online Access:	https://www.mdpi.com/2218-0532/93/2/19
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