Oral curative therapeutic study of N-nitrosodiethylamine-induced mouse liver damage of chitosan-coated ursolic acid niosomes

Oral curative therapeutic study of N-nitrosodiethylamine-induced mouse liver damage of chitosan-coated ursolic acid niosomes

Abstract Ursolic acid (UA), classified as a Biopharmaceutics Classification System (BCS) class IV compound, exhibits hepatoprotective, anti-inflammatory, and anticancer activities. In previous studies, niosomes have been shown to increase the bioavailability of BCS class IV drugs. Chitosan coating a...

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Main Authors: Andang Miatmoko, Ahmad Aziz Jauhari, Amelia Anneke Faradisa, Devy Maulidya Cahyani, Berlian Sarasitha Hariawan, Joni Susanto, Thaigarajan Parumasivam, Esti Hendradi, Retno Sari
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Scientific Reports
Subjects:
Anticancer
Ursolic acid
Niosome
Liver damage
NDEA
Curative
Online Access:https://doi.org/10.1038/s41598-025-04571-7
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https://doi.org/10.1038/s41598-025-04571-7

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