Brassinosteroid-Mediated Resistance to Cobalt-Induced Toxicity by Regulating Hormonal Balance, Cellular Metabolism, and Antioxidant Defense in Maize

Brassinosteroids (BRs) play an essential role in regulating plant metabolic pathways that influence growth, development, and stress responses. However, their role in alleviating cobalt (Co) stress has not been extensively studied. This research aimed to assess the impact of exogenous BRs (0.1 µM) on...

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Main Authors: Abdul Salam, Jinzhe Chang, Liupeng Yang, Muhammad Zeeshan, Anas Iqbal, Ali Raza Khan, Muhammad Siddique Afridi, Zaid Ulhassan, Wardah Azhar, Zhixiang Zhang, Peiwen Zhang
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Plants
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Online Access:https://www.mdpi.com/2223-7747/14/13/2076
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Summary:Brassinosteroids (BRs) play an essential role in regulating plant metabolic pathways that influence growth, development, and stress responses. However, their role in alleviating cobalt (Co) stress has not been extensively studied. This research aimed to assess the impact of exogenous BRs (0.1 µM) on maize subjected to Co stress (300 µM) in a hydroponic experiment. The results indicated that BR supplementation significantly decreased the accumulation of H<sub>2</sub>O<sub>2</sub> by 17.79 and 16.66%, O<sub>2</sub><sup>•−</sup> by 28.5 and 21.48%, and MDA by 37.5 and 37.9% in shoot and root, respectively, as compared to Co stress alone. Additionally, BRs enhanced endogenous levels of BRs (31.16%) and growth hormones (IAA 50.8%, JA 57.8%, GA 52.5%), and reduced Co contents by 26.3% in roots and 36.1% in shoots. BRs enhanced antioxidant enzyme activity both in the shoot and root, leading to reduced ROS levels as confirmed by laser scanning confocal microscopy. Furthermore, BRs increased phenols, flavonoids, and soluble sugars, and elevated total protein content. Observations from transmission electron microscopy indicated reduced ultrastructural damage in plants treated with BRs under Co stress. Taken together, this study highlights the role of BRs in alleviating Co stress in maize, demonstrating their efficiency in enhancing stress tolerance by modulating hormone levels and key metabolic processes.
ISSN:2223-7747