The dimeric conformation of PRRSV nsp1α is important for its ability to regulate viral RNA synthesis
Abstract PRRSV nsp1α, the first viral protein translated in virus-infected cells, is released from viral polyprotein 1a through autocleavage. It plays important roles in viral replication, the suppression of the host innate immune response, and the modulation of cell-mediated immune responses. Nsp1α...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-05-01
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| Series: | Veterinary Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13567-025-01537-5 |
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