Pre-pregnancy obesity is associated with an altered maternal metabolome and reduced Flt3L expression in preterm birth

Pre-pregnancy obesity is associated with an altered maternal metabolome and reduced Flt3L expression in preterm birth

Abstract Mechanisms linking pre-pregnancy obesity to increased preterm birth risk are unclear. Here, we examined the impact of pre-pregnancy obesity on metabolites, Fms-related tyrosine kinase 3 ligand (Flt3L), and proinflammatory cytokine profiles in preterm birth. We used cytokine bead array, ELIS...

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Main Authors: Ismail Sebina, Charles Bidgood, Felicity Stalley, Gunter Hartel, Terra Stark, Leonie Callaway, Akwasi Amoako, Christoph Lehner, Marloes Dekker Nitert, Simon Phipps
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-81194-4
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https://doi.org/10.1038/s41598-024-81194-4

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