A Comprehensive Review of the Role of the Microbiota–Gut–Brain Axis via Neuroinflammation: Advances and Therapeutic Implications for Ischemic Stroke

A Comprehensive Review of the Role of the Microbiota–Gut–Brain Axis via Neuroinflammation: Advances and Therapeutic Implications for Ischemic Stroke

The human gastrointestinal tract harbors a complex and diverse microbial community. Emerging evidence has revealed bidirectional communication between the gut microbiome and the central nervous system, termed the “microbiota–gut–brain axis”. This axis serves as a critical regulator of glial cell fun...

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Bibliographic Details
Main Authors: Hui Guo, Xiang Tang, Xinyi He, Yizhen Weng, Quanquan Zhang, Qi Fang, Lulu Zhang
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Biomolecules
Subjects:
ischemic stroke
microbiome–gut–brain axis
neuroinflammation
gut-derived metabolites
neurotransmitters
microglia
Online Access:https://www.mdpi.com/2218-273X/15/7/920
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